Affordable and Versatile Room Temperature Sterilizers



Low Temperature.

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Our Anprolene sterilizers have the most delicate 100% EO sterilization cycle on the market. Room temperature sterilization, no steam injection, no deep vacuum, and uses only 17.6 g of gas – all in a convenient tabletop cabinet.

AN74i and bag diagram
Anprolene's proven reliability

Anprolene uses Ethylene Oxide sterilization, the  gold standard in low temperature sterilization because of its unparalleled gentleness and material compatibility

Add that to our exclusive EO-FCT system, and you have  a winning combination in a sterilizer that has been adopted by over 5,000 facilities worldwide.

This is the most inexpensive and versatile low temperature sterilizer available!

Anprolene sterilizers now features a number of important improvements. They include: more powerful ventilation and purge pumps, unique active aeration system, digital display tracks cycle progress, temperature sensor monitors room conditions during each cycle, microprocessor monitors cycle and automatically restores system in case of power failure.

Unmatched Sterilization Compatibility

Anprolene’s 100% EO system sterilizes at room temperature without external vacuum lines or steam generator. Protects your most delicate instruments, electronics, drills, fiber optics, cameras and plastic or rubber items…

Most any item with the exception of food, drugs or liquids can be sterilized with Anprolene.


Our exclusive flexible chamber technology ensures that you get the most out of your sterilizer: maximum performance with the least amount of gas.


Select and monitor the sterilization cycle from an intuitive user interface.

Anprolene abator

Tabletop design requires only a 110V or 220V electrical outlet and a 1″ exhaust line.

Optional abator available.

Anprolene AN74i

The Andersen Anprolene Key Operator Certification Program is available free of charge for the lifetime of your sterilizer.

Three Models to Choose From

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Using the Anprolene Sterilizer

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Resources for existing Anprolene AN74 users

Andersen provides free training for as many operators as required,
for the lifetime of any of its sterilizers.


We have everything you need to compete a cycle.  Please refer to our Anprolene Accessories page for a comprehensive list.

Time, temperature and EO concentration are essential to successful sterilization. Dosimeter integrators present visual assurance that all these parameters have been fulfilled. Dosimeters change color in proportion to the dose of sterilant they contact. View results immediately after sterilization. No laboratory culture is necessary. Use one Dosimeter per cycle. (Not a BI substitute).

Designed specifically for use with Andersen EOGas™ and Anprolene® systems, this unique device ensures adequate Relative Humidity (RH) during the sterilization cycle. Each single use pre-moistened 2″ x 2″ Humidichip releases up to 4 grams of water vapor.  Employ Humidchip® with a reusable Humiditube™ in each sterilization cycle.

The Anprolene system uses unique plastic sterilization liner bags and individual gas ampoules. We offer two different bag/ampoule combinations to match the size of your sterilization load. You never use more gas than you have to.

Frequently Asked Questions

Anprolene sterilizes in 12 or 24 hours depending on the load.

No. Our tabletop unit only needs a 1 inch port to the outside.

No. It is very easy and convenient to install and comes in a tabletop package.

No. EO is the most gentle and compatible sterilization method available. Perfect for your most sensitive instruments.

Yes. We offer training free of charge for the life of the sterilizer.

No. EO is used in many different household products and has a similar chemical ratings as other products such as hydrogen peroxide.

No. All Anprolene model sterilizers are tabletop in size.

Made in USA

Andersen sterilizers are 100% US made. Proudly designed and manufactured at our headquarters in Haw River, North Carolina.

When all else fails, EO succeeds.

Why does Anprolene use EO as a sterilant?

We have the sterilizer that meets your needs!

Anprolene Best Value


Three sizes to choose from. Room temperature. Tabletop cabinets with active aeration. The least expensive, low temperature sterilization cabinets available.

EOGas 4 Best Speed

EOGas 4

50⁰C or 30⁰C cycle, high efficiency EO Sterilizer. Tabletop cabinet with active aeration. Sterilizes in as little as 3.5 hours. The fastest EO sterilizer available.

EOGas 3 Best Capacity

EOGas 3

Two sizes to choose from. 40-55⁰C cycles, free-standing cabinets run up to 10 independent 60L loads at any time. All cycles deliver 10-6 SAL.

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